Ahmed Kamal, Rajender, Methuku Kashi Reddy, Vangala Santhosh Reddy and Gajjela Bharath Kumar Pages 177 - 192 ( 16 )
A series of twelve benzopyran linked pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) have been synthesized. They exhibit significant DNA-binding activity and excellent cytotoxic activity against various human cancer cell lines.
Cytotoxicity, DNA-Binding affinity, 2, 2-Dimethyl benzopyran, Pyrrolo[2, 1-c][1, 4]benzodiazepines and Piperazine
Division of Organic Chemistry, Centre for Chemical Biology, Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 607, India.