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New Lanthanide Complexes with Antioxidant Activity

[ Vol. 4 , Issue. 4 ]

Author(s):

Irena Kostova, Maria Traykova and Vinod K. Rastogi   Pages 371 - 378 ( 8 )

Abstract:


The cerium (III), lanthanum (III) and neodymium (III) complexes of 5-aminoorotic acid were synthesized and their structures were determined by means of theoretical study, spectral and physicochemical analysis. Significant differences in the spectra of the complexes were observed as compared to the spectra of the ligand. The ligand and the complexes were tested for the antioxidant activity. The results obtained indicate that the tested compounds exerted a considerable antioxidant effect upon the evaluated radicals formation in the blood plasma of Wistar rat.

Keywords:

Lanthanide (III) complexes, 5-Aminoorotic acid, antioxidant activity

Affiliation:

Department of Chemistry,Faculty of Pharmacy, Medical University, 2 Dunav St., Sofia 1000,Bulgaria.



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