E-Pub Full Text Articles

Synthesis and Biological Evaluation of Novel 2,3-disubstituted Benzofuran Analogues of GABA as Neurotropic Agents

Author(s): Arturo Coaviche-Yoval, Hector Luna, Ricardo Tovar-Miranda, Marvin Antonio Soriano-Ursua and Jose G. Trujillo-Ferrara*
Pages: 1-10 (10)
Synthesis of New Thiosemicarbazones and Semicarbazones Containing the 1,2,3-1H-triazole-isatin Scaffold: Trypanocidal, Cytotoxicity, Electrochemical Assays, and Molecular Docking

Author(s): Bianca N. M. Silva, Policarpo A. Sales , Alvaro J. Romanha, Silvane M. F. Murta, Camilo H. S. Lima, Magaly G. Albuquerque, Eliane D'Elia, Jose G. de Aquino, Vitor F. Ferreira, Fernando C. Silva, Angelo C. Pinto and Barbara V. Silva*
Pages: 1-17 (17)
Ligand-Based Drug Design: Synthesis and Biological Evaluation of Substituted Benzoin Derivatives as Potential Antitumor Agents

Author(s): Dima A. Sabbah*, Ameerah Hasan Ibrahim, Wamidh H. Talib, Khalid M. Alqaisi, Kamal Sweidan, Sanaa K. Bardaweel, Ghassan Abu Sheikha, Haizhen A. Zhong, Eveen Al-Shalabi, Reema Abu Khalaf and Mohammad S. Mubarak
Pages: 1-13 (13)
Synthesis and Biological Evaluation of Novel Osthol Derivatives as Potent Cytotoxic Agents

Author(s): Saleem Farooq*, Javid A. Banday*, Aashiq Hussain, Momina Nazir, Mushtaq A. Qurishi, Abid Hamid and S. Koul*
Pages: 1-12 (12)
Synthesis, 2D-QSAR Studies and Biological Evaluation of Quinazoline Derivatives as Potent Anti-Trypanosoma cruzi Agents

Author(s): Mariela Bollini, Ana María Bruno*, María Eugenia Niño, Juan José Casal, Leandro Daniel Sasiambarrena, Damián Ariel González Valdez, Leandro Battini, Vanesa Rocío Puente and María Elisa Lombardo
Pages: 1-12 (12)
Essential Oil from Lippia origanoides (Verbenaceae): Haemostasis and Enzymes Activity Alterations

Author(s): Maria Luisa Teixeira, Silvana Marcussi, Danubia Aparecida de Carvalho Selvati Rezende, Maisa Lamounier Magalhaes, David Lee Nelson and Maria das Gracas Cardoso
Pages: 1-8 (8)
New N,C-Diaryl-1,2,4-triazol-3-ones: Synthesis and Evaluation as Anticancer Agents

Author(s): Dolores Santa Maria*, Rosa M. Claramunt, Jose Elguero, Miguel Carda, Eva Falomir and Celia Martin-Beltran
Pages: 1-13 (13)
Anticancer Activity and Topoisomerase II Inhibition of Naphthalimides with ω-Hydroxylalkylamine Side-Chains of Different Lengths

Author(s): Mateusz D. Tomczyk, Anna Byczek Wyrostek, Klaudia Strama, Martyna Wawszków, Przemysław Kasprzycki and Krzysztof Z. Walczak*
Pages: 1-10 (10)
New Hybrid Scaffolds based on Hydrazinyl Thiazole Substituted Coumarin; As Novel Leads of Dual Potential; In Vitro α-Amylase Inhibitory and Antioxidant (DPPH and ABTS Radical Scavenging) Activities

Author(s): Uzma Salar, Khalid Mohammed Khan*, Sridevi Chigurupati, Shazia Syed, Shantini Vijayabalan, Abdul Wadood, Muhammad Riaz, Mehreen Ghufran and Shahnaz Perveen
Pages: 1-15 (15)
Antiproliferative Activity and Characterization of Metabolites of Aspergillus nidulans: An Endophytic Fungus from Nyctanthes arbor-tristis Linn. Against Three Human Cancer Cell Lines

Author(s): Talea Sana, Bina S. Siddiqui*, Saleem Shahzad, Ahsana D. Farooq, Faheema Siddiqui, Samia Sattar and Sabira Begum
Pages: 1-8 (8)
Design, Synthesis, and Biological Evaluation of Novel Thiazolyl Substituted Bis-pyrazole Oxime Derivatives with Potent Antitumor Activities by Selectively Inducing Apoptosis and ROS in Cancer Cells

Author(s): Biao Xiong, Shi Chen, Peng Zhu, Meili Huang, Weijie Gao, Rui Zhu, Jianqiang Qian, Yanfu Peng, Yanan Zhang, Hong Dai and Yong Ling*
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ZnO Nanoparticles Catalyst in the Synthesis of Bioactive Fused Pyrimidines as Anti-breast Cancer Agents Targeting VEGFR-2

Author(s): Dina H. Dawood, Eman M. H. Abbas, Thoraya A. Farghaly*, Mamdouh M. Ali and Mohammed F. Ibrahim
Pages: 1-10 (10)
N-(Sulfamoylbenzoyl)-L-proline Derivatives as Potential Non-

Author(s): Xinyu Liu, Shengjie Dong, Yuru Ma, Hu Xu, Hongxia Zhao* and Qingzhi Gao*
Pages: 1-11 (11)
Design, Synthesis and Investigation of New Diphenyl Substituted Pyridazinone Derivatives as Both Cholinesterase and Aβ-Aggregation Inhibitors

Author(s): Burcu Kilic, Merve Erdogan, Hayrettin O. Gulcan, Fatma Aksakal, Nihan Oruklu, E. Umit Bagriacik and Deniz S. Dogruer*
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Benzophenone Esters and Sulfonates: Synthesis and their Potential as Antiinflammatory Agents

Author(s): Arshia, Almas Jabeen, Aisha Faheem, Khalid Mohammed Khan*, Shazia Shah and Shahnaz Perveen
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Synthesis and Evaluation of the in vitro Antimicrobial Activity of Triazoles, Morpholine and Thiosemicarbazones

Author(s): Felipe R. S. Santos, Jessica T. Andrade, Carla D. F. Sousa, Joice S. Fernandes, Lucas F. Carmo, Marcelo G. F. Araujo, Jaqueline M. S. Ferreira and Jose A. F. P. Villar*
Pages: 1-13 (13)
4-Hydroxy-2-pyridone Derivatives and the δ-pyrone Isostere as Novel Agents Against Mycobacterium smegmatis Biofilm Inhibitors

Author(s): Maheshkumar R. Borkar, Santosh Nandan*, M N Harish Kumar , Jayashree Puttur, M Jisha , Dipankar Chatterji and Evans C. Coutinho *
Pages: 1-10 (10)
Synthesis & Anticancer Evaluation of New Substituted 2-(3,4- Dimethoxyphenyl)benzazoles

Author(s): Cigdem Karaaslan , Yalcin Duydu, Aylin Ustundag , Can Ozgur Yalcin, Banu Kaskatepe and Hakan Goker*
Pages: 1-11 (11)
Synthesis and Structural Elucidation of Novel Benzothiazole Derivatives as Anti-tubercular Agents: In-silico Screening for Possible Target Identification

Author(s): Katharigatta N. Venugopala*, Sandeep Chandrashekharappa, Melendhran Pillay, Subhrajyoti Bhandary, Mahmoud Kandeel, Fawzi M. Mahomoodally , Mohamed A. Morsy, Deepak Chopra , Bandar E. Aldhubiab, Mahesh Attimarad, Osama I. Alwassil , Sree Harsha and Koleka Mlisana
Pages: 1-16 (16)
Neuropharmacological Screening of Chiral and Non-chiral Phthalimide- Containing Compounds in Mice: in vivo and in silico Experiments

Author(s): Carolina Campos-Rodriguez, Jose G. Trujillo-Ferrara*, Ameyali Alvarez-Guerra, Iran M. Cumbres Vargas, Roberto I. Cuevas-Hernandez, Erik Andrade-Jorge, Sergio Zamudio and Eduardo Ramirez-San Juan*
Pages: 1-17 (17)
The Evaluation of Metal Co-ordinating Bis-Thiosemicarbazones as Potential Anti-malarial Agents

Author(s): Fady N. Akladios, Scott D. Andrew, Samantha J. Boog, Carmen de Kock, Richard K. Haynes and Christopher J. Parkinson*
Pages: 1-8 (8)
Pyrano[3,2-c]quinoline Derivatives as New Class of α-glucosidase Inhibitors to Treat Type 2 Diabetes: Synthesis, in vitro Biological Evaluation and Kinetic Study

Author(s): Zahra Heydari, Maryam Mohammadi-Khanaposhtani, Somaye Imanparast, Mohammad Ali Faramarzi, Mohammad Mahdavi *, Parviz Rashidi Ranjbar* and Bagher Larijani
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Design, Synthesis and Biological Evaluation of 1H-1,2,3-Triazole-Linked- 1H

Author(s): Carolina S. Bortolot, Luana da S. M. Forezi, Roberta K. F. Marra, Marcelo I. P. Reis, Barbara V. F. e Sa, Ricardo Imbroisi Filho, Zeinab Ghasemishahrestani, Mauro Sola-Penna, Patricia Zancan, Vitor F. Ferreira* and Fernando de C. da Silva*
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Exploration of (hetero)aryl Derived Thienylchalcones for Antiviral and Anticancer Activities

Author(s): Vikrant Patil, Siddappa A. Patil*, Renukadevi Patil, Alejandro Bugarin, Kenneth Beaman and Shivaputra A. Patil*
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Sorbinil, an Aldolase Reductase Inhibitor, in Fighting Against Diabetic Complications

Author(s): Qi Huang, Qiong Liu and Dongsheng Ouyang*
Pages: 1-5 (5)
Pyrazole and imidazo[1,2-b]pyrazole Derivatives as New Potential Antituberculosis Agents

Author(s): Elda Meta, Chiara Brullo*, Michele Tonelli, Scott G. Franzblau, Yuehong Wang, Rui Ma, Wan Baojie , Beatrice Silvia Orena, Maria Rosalia Pasca and Olga Bruno
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E-Pub Full Text Articles

Synthesis and Biological Evaluation of Novel 2,3-disubstituted Benzofuran Analogues of GABA as Neurotropic Agents

Synthesis of New Thiosemicarbazones and Semicarbazones Containing the 1,2,3-1H-triazole-isatin Scaffold: Trypanocidal, Cytotoxicity, Electrochemical Assays, and Molecular Docking

Ligand-Based Drug Design: Synthesis and Biological Evaluation of Substituted Benzoin Derivatives as Potential Antitumor Agents

Synthesis and Biological Evaluation of Novel Osthol Derivatives as Potent Cytotoxic Agents

Synthesis, 2D-QSAR Studies and Biological Evaluation of Quinazoline Derivatives as Potent Anti-Trypanosoma cruzi Agents

Essential Oil from Lippia origanoides (Verbenaceae): Haemostasis and Enzymes Activity Alterations

New N,C-Diaryl-1,2,4-triazol-3-ones: Synthesis and Evaluation as Anticancer Agents

Anticancer Activity and Topoisomerase II Inhibition of Naphthalimides with ω-Hydroxylalkylamine Side-Chains of Different Lengths

New Hybrid Scaffolds based on Hydrazinyl Thiazole Substituted Coumarin; As Novel Leads of Dual Potential; In Vitro α-Amylase Inhibitory and Antioxidant (DPPH and ABTS Radical Scavenging) Activities

Antiproliferative Activity and Characterization of Metabolites of Aspergillus nidulans: An Endophytic Fungus from Nyctanthes arbor-tristis Linn. Against Three Human Cancer Cell Lines

Design, Synthesis, and Biological Evaluation of Novel Thiazolyl Substituted Bis-pyrazole Oxime Derivatives with Potent Antitumor Activities by Selectively Inducing Apoptosis and ROS in Cancer Cells

ZnO Nanoparticles Catalyst in the Synthesis of Bioactive Fused Pyrimidines as Anti-breast Cancer Agents Targeting VEGFR-2

N-(Sulfamoylbenzoyl)-L-proline Derivatives as Potential Non-

Design, Synthesis and Investigation of New Diphenyl Substituted Pyridazinone Derivatives as Both Cholinesterase and Aβ-Aggregation Inhibitors

Benzophenone Esters and Sulfonates: Synthesis and their Potential as Antiinflammatory Agents

Synthesis and Evaluation of the in vitro Antimicrobial Activity of Triazoles, Morpholine and Thiosemicarbazones

4-Hydroxy-2-pyridone Derivatives and the δ-pyrone Isostere as Novel Agents Against Mycobacterium smegmatis Biofilm Inhibitors

Synthesis & Anticancer Evaluation of New Substituted 2-(3,4- Dimethoxyphenyl)benzazoles

Synthesis and Structural Elucidation of Novel Benzothiazole Derivatives as Anti-tubercular Agents: In-silico Screening for Possible Target Identification

Neuropharmacological Screening of Chiral and Non-chiral Phthalimide- Containing Compounds in Mice: in vivo and in silico Experiments

The Evaluation of Metal Co-ordinating Bis-Thiosemicarbazones as Potential Anti-malarial Agents

Pyrano[3,2-c]quinoline Derivatives as New Class of α-glucosidase Inhibitors to Treat Type 2 Diabetes: Synthesis, in vitro Biological Evaluation and Kinetic Study

Design, Synthesis and Biological Evaluation of 1H-1,2,3-Triazole-Linked- 1H

Exploration of (hetero)aryl Derived Thienylchalcones for Antiviral and Anticancer Activities

Sorbinil, an Aldolase Reductase Inhibitor, in Fighting Against Diabetic Complications

Pyrazole and imidazo[1,2-b]pyrazole Derivatives as New Potential Antituberculosis Agents